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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Overdose: Which Medications Are Safest? (351 Drugs Compared)

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351 medications are used for Overdose, with 1,625 combined adverse event reports. The most reported drugs for Overdose are NALOXONE and ACETAMINOPHEN.

1,625
Total Reports
351
Drugs Used

All Medications for Overdose Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
NALOXONE Naloxone Hydrochloride 585 779 1,033 27.2%
ACETAMINOPHEN Hydrocodone Bitartrate and Acetaminophen 141 30,085 50,046 22.0%
AMLODIPINE Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide 80 10,161 26,787 15.7%
ACETYLCYSTEINE Acetylcysteine 70 421 1,199 17.5%
QUETIAPINE Quetiapine 55 13,610 31,386 18.6%
DIPHENHYDRAMINE Allergy Relief 37 10,508 6,849 40.7%
IBUPROFEN equate ibuprofen 35 6,705 29,386 7.7%
INSULIN NOS - 30 1,071 2,441 17.6%
CALCIUM Calcium Gluconate 29 4,138 7,578 26.4%
CITALOPRAM HYDROBROMIDE Citalopram Hydrobromide 27 6,745 9,074 24.9%
ACTIVATED CHARCOAL THE FLOWER REMEDY Get Up and Go 26 94 207 31.9%
BUPROPION Bupropion Hydrochloride (XL) 26 8,577 10,246 24.1%
OLANZAPINE Olanzapine 26 5,535 21,934 10.8%
VERAPAMIL Verapamil Hydrochloride 26 2,630 3,576 28.2%
LORAZEPAM Lorazepam 25 6,187 15,431 18.5%
METHYLENE BLUE Methylene blue 25 165 536 19.5%
GLUCAGON Glucagon 24 206 410 14.2%
VASOPRESSIN Vasopressin 24 801 1,195 41.0%
VENLAFAXINE Venlafaxine Hydrochloride 24 7,521 15,749 15.7%
ZOLPIDEM Zolpidem Tartrate 24 3,908 7,033 18.2%

View all 351 drugs →

Most Reported Drugs for Overdose

#1 most reported
#2 most reported
#3 most reported