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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Sinus congestion: Which Medications Are Safest? (154 Drugs Compared)

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154 medications are used for Sinus congestion, with 1,851 combined adverse event reports. The most reported drugs for Sinus congestion are PSEUDOEPHEDRINE and CETIRIZINE.

1,851
Total Reports
154
Drugs Used

All Medications for Sinus congestion Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
PSEUDOEPHEDRINE CareOne Nasal and Sinus Decongestant 398 3,768 4,451 28.8%
CETIRIZINE Cetirizine 169 4,787 8,423 10.0%
IBUPROFEN\PHENYLEPHRINE - 122 0 8 N/A
FLUTICASONE ADVAIR DISKUS 103 1,043 3,658 3.3%
LORATADINE\PSEUDOEPHEDRINE - 102 4 84 0.1%
CETIRIZINE\PSEUDOEPHEDRINE - 93 2,361 2,599 37.5%
LORATADINE Curist Allergy Relief 71 372 1,472 1.5%
GUAIFENESIN Guaifenesin and Pseudoephedrine HCl 59 158 371 2.0%
OXYMETAZOLINE Nasal 57 31 120 0.7%
DEXTROMETHORPHAN HYDROBROMIDE\GUAIFENESIN - 49 66 237 1.0%
FEXOFENADINE\PSEUDOEPHEDRINE - 40 8 71 0.2%
TRIAMCINOLONE ACETONIDE Triamcinolone Acetonide 39 1,874 3,276 11.2%
AZELASTINE Azelastine Hydrochloride 37 12 89 0.2%
NAPROXEN\PSEUDOEPHEDRINE - 35 2 4 0.5%
CLARITIN-D-24 - 29 0 0 N/A
GUAIFENESIN\PSEUDOEPHEDRINE - 28 14 15 1.5%
FEXOFENADINE Fexofenadine HCl 24 80 535 0.4%
ACETAMINOPHEN Hydrocodone Bitartrate and Acetaminophen 22 30,085 50,046 22.0%
FLUTICASONE FUROATE Fluticasone Furoate Ellipta 19 334 1,410 4.3%
IBUPROFEN\PSEUDOEPHEDRINE - 18 5 103 0.6%

View all 154 drugs →

Most Reported Drugs for Sinus congestion

#1 most reported
#2 most reported
#3 most reported