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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Surgery: Which Medications Are Safest? (529 Drugs Compared)

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529 medications are used for Surgery, with 3,529 combined adverse event reports. The most reported drugs for Surgery are OXYCODONE and MORPHINE.

3,529
Total Reports
529
Drugs Used

All Medications for Surgery Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
OXYCODONE Oxycodone Hydrochloride 339 55,140 21,279 28.9%
MORPHINE Morphine Sulfate 141 38,212 17,386 31.7%
PROPOFOL Propofol 141 1,970 6,577 12.3%
COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTEIN C\PROTEIN S HUMAN\PROTHROMBIN - 132 313 158 27.1%
ROCURONIUM ROCURONIUM BROMIDE 130 424 1,982 6.5%
BUPIVACAINE Bupivacaine Hydrochloride 129 466 2,367 4.1%
DEXAMETHASONE Dexamethasone Sodium Phosphate 127 22,319 51,311 17.8%
ACETAMINOPHEN\OXYCODONE - 102 31,342 7,703 31.5%
FENTANYL FENTANYL 101 42,491 15,153 45.0%
ACETAMINOPHEN\HYDROCODONE - 95 31,727 6,901 29.1%
POLYETHYLENE GLYCOL 3350 Polyethylene Glycol 3350, Sodium Chloride, Sodium Bicarbonate and Potassium Chloride - Unflavored 89 478 1,116 1.3%
CEFAZOLIN Cefazolin 84 345 2,331 6.7%
HYDROMORPHONE Hydromorphone Hydrochloride 80 28,491 10,395 34.1%
ENOXAPARIN Enoxaparin Sodium 74 3,423 10,898 13.7%
LIDOCAINE Burn Relief 71 1,738 5,570 7.6%
RIVAROXABAN Rivaroxaban 70 19,233 70,513 14.7%
TRAMADOL ConZip 68 14,555 19,235 19.2%
HEPARIN Heparin Sodium 63 3,150 7,788 17.3%
SEVOFLURANE Sojourn 58 272 1,413 6.3%
VANCOMYCIN Vancomycin Hydrochloride 55 5,348 15,776 15.8%

View all 529 drugs →

Most Reported Drugs for Surgery

#1 most reported
#2 most reported
#3 most reported