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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Weight decreased: Which Medications Are Safest? (371 Drugs Compared)

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371 medications are used for Weight decreased, with 14,773 combined adverse event reports. The most reported drugs for Weight decreased are TIRZEPATIDE and PHENTERMINE\TOPIRAMATE.

14,773
Total Reports
371
Drugs Used

All Medications for Weight decreased Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
TIRZEPATIDE Zepbound 2,625 455 5,527 0.5%
PHENTERMINE\TOPIRAMATE - 2,129 9 170 0.2%
SEMAGLUTIDE WEGOVY 1,680 792 11,258 1.3%
LORCASERIN - 1,640 15 187 0.6%
LIRAGLUTIDE Victoza 1,460 994 4,819 4.3%
ORLISTAT Xenical 960 31 329 0.5%
ALLI - 795 0 14 N/A
PHENTERMINE Phentermine Hydrochloride 452 222 399 12.5%
DULAGLUTIDE Trulicity 429 1,054 6,536 1.4%
BUPROPION\NALTREXONE - 426 30 628 0.4%
TOPIRAMATE Topiramate 251 3,527 7,098 12.3%
METFORMIN Metformin Hydrochloride 226 11,550 40,702 12.7%
EXENATIDE Exenatide 197 1,228 2,512 3.9%
QSYMIA - 174 1 3 0.3%
BELVIQ - 146 1 7 0.3%
DAPAGLIFLOZIN PROPANEDIOL FARXIGA 97 3,694 2,425 21.9%
BUPROPION Bupropion Hydrochloride (XL) 85 8,577 10,246 24.1%
SIBUTRAMINE - 80 9 27 6.4%
ALBIGLUTIDE - 71 33 323 0.4%
SILDENAFIL Sildenafil 65 4,979 8,623 14.1%

View all 371 drugs →

Most Reported Drugs for Weight decreased

#1 most reported
#2 most reported
#3 most reported