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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

All Drugs Associated with Drug tolerance increased

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45 drugs have been associated with Drug tolerance increased in FAERS reports.

Drug Reports Deaths Hosp. Life-Threat.
OXYCODONE 180 15 36 4
MORPHINE 95 7 28 4
ACETAMINOPHEN\OXYCODONE 92 5 18 5
ACETAMINOPHEN\HYDROCODONE 87 3 19 5
HYDROMORPHONE 86 7 23 5
ADALIMUMAB 67 0 10 0
TRAMADOL 54 0 8 1
FENTANYL 45 4 10 0
ALPRAZOLAM 33 3 10 5
DIAMORPHINE 30 3 6 1
ACETAMINOPHEN\OXYCODONE\OXYCODONE TEREPHTHALATE 28 6 5 4
HYDROCODONE 24 2 4 4
PREGABALIN 24 1 5 0
BUPRENORPHINE 23 2 6 0
GABAPENTIN 19 0 2 0
COCAINE 17 1 8 1
METHADONE 17 2 6 0
OXYMORPHONE 15 2 0 0
DIAZEPAM 14 0 5 2
CETIRIZINE 13 0 0 0
CODEINE 13 1 7 0
ZOLPIDEM 12 1 2 0
BUPRENORPHINE\NALOXONE 11 1 5 0
INFLIXIMAB 10 0 1 0
ETANERCEPT 8 0 0 0
LORAZEPAM 8 0 0 1
METHOTREXATE 8 0 0 0
ACETAMINOPHEN\TRAMADOL 7 0 0 0
ALCOHOL 7 1 1 0
AMPHETAMINE ASPARTATE\AMPHETAMINE\DEXTROAMPHETAMINE SACCHARATE\DEXTROAMPHETAMINE 7 0 1 0
CARISOPRODOL 7 2 2 0
CLONAZEPAM 7 0 1 2
LISDEXAMFETAMINE DIMESYLATE 7 0 0 0
NICOTINE 7 0 5 0
PREDNISONE 7 2 0 0
USTEKINUMAB 7 0 2 0
ACETAMINOPHEN\CODEINE 6 1 0 0
AMPHETAMINE 6 0 5 0
CAFFEINE 6 0 6 0
CANNABIS SATIVA SUBSP. INDICA TOP 6 0 1 0
METHAMPHETAMINE 6 0 0 0
NAPROXEN 6 0 0 0
PSILOCYBINE 6 0 6 0
TOFACITINIB 6 0 0 0
INTERFERON BETA-1A 5 0 3 0