Guanylate Cyclase Activators [MoA]: Side Effects & Safety Data for 2 Drugs
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Guanylate Cyclase Activators [MoA] includes 2 drugs with a combined 14,299 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
2
Drugs in Class
14,299
Combined Reports
All Guanylate Cyclase Activators [MoA] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| LINACLOTIDE | Linzess | 13,332 | 358 | 756 | 2.7% |
| PLECANATIDE | Trulance Immediate release | 967 | 45 | 50 | 4.7% |
Common Side Effects in Guanylate Cyclase Activators [MoA] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Diarrhoea | 3,936 | 8 |
| Drug ineffective | 3,660 | 3 |
| Off label use | 2,643 | 16 |
| Constipation | 1,215 | 4 |
| Abdominal distension | 944 | 2 |
| Abdominal pain | 745 | 3 |
| Abdominal pain upper | 641 | 1 |
| Flatulence | 612 | 0 |
| Inappropriate schedule of product administration | 564 | 0 |
| Nausea | 511 | 3 |