Does 5-FU Cause Interstitial lung disease? 7 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 7 reports of Interstitial lung disease have been filed in association with 5-FU. This represents 4.4% of all adverse event reports for 5-FU.
7
Reports of Interstitial lung disease with 5-FU
4.4%
of all 5-FU reports
2
Deaths
1
Hospitalizations
How Dangerous Is Interstitial lung disease From 5-FU?
Of the 7 reports, 2 (28.6%) resulted in death, 1 (14.3%) required hospitalization, and 1 (14.3%) were considered life-threatening.
Is Interstitial lung disease Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for 5-FU. However, 7 reports have been filed with the FAERS database.
What Other Side Effects Does 5-FU Cause?
Diarrhoea (21)
Disease progression (14)
Nausea (13)
Stomatitis (12)
Vomiting (12)
Dehydration (11)
Neutropenia (11)
Fatigue (9)
Hypertension (9)
Mucosal inflammation (9)
What Other Drugs Cause Interstitial lung disease?
METHOTREXATE (3,049)
RITUXIMAB (2,458)
PEMBROLIZUMAB (2,113)
PREDNISONE (1,850)
CYCLOPHOSPHAMIDE (1,725)
NIVOLUMAB (1,538)
AMIODARONE (1,421)
DOXORUBICIN (1,352)
ETANERCEPT (1,267)
ADALIMUMAB (1,250)
Which 5-FU Alternatives Have Lower Interstitial lung disease Risk?
5-FU vs 6-ACETYLMORPHINE
5-FU vs ABACAVIR
5-FU vs ABACAVIR\DOLUTEGRAVIR\LAMIVUDINE
5-FU vs ABACAVIR\LAMIVUDINE
5-FU vs ABACAVIR\LAMIVUDINE\ZIDOVUDINE