Does METHOTREXATE Cause Interstitial lung disease? 3,049 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 3,049 reports of Interstitial lung disease have been filed in association with METHOTREXATE (Methotrexate). This represents 1.2% of all adverse event reports for METHOTREXATE.
3,049
Reports of Interstitial lung disease with METHOTREXATE
1.2%
of all METHOTREXATE reports
358
Deaths
1,122
Hospitalizations
How Dangerous Is Interstitial lung disease From METHOTREXATE?
Of the 3,049 reports, 358 (11.7%) resulted in death, 1,122 (36.8%) required hospitalization, and 299 (9.8%) were considered life-threatening.
Is Interstitial lung disease Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 3,049 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Interstitial lung disease?
RITUXIMAB (2,458)
PEMBROLIZUMAB (2,113)
PREDNISONE (1,850)
CYCLOPHOSPHAMIDE (1,725)
NIVOLUMAB (1,538)
AMIODARONE (1,421)
DOXORUBICIN (1,352)
ETANERCEPT (1,267)
ADALIMUMAB (1,250)
TOCILIZUMAB (1,229)
Which METHOTREXATE Alternatives Have Lower Interstitial lung disease Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA