Does ABACAVIR Cause Mitochondrial toxicity? 121 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 121 reports of Mitochondrial toxicity have been filed in association with ABACAVIR (Abacavir Sulfate). This represents 2.8% of all adverse event reports for ABACAVIR.
121
Reports of Mitochondrial toxicity with ABACAVIR
2.8%
of all ABACAVIR reports
2
Deaths
3
Hospitalizations
How Dangerous Is Mitochondrial toxicity From ABACAVIR?
Of the 121 reports, 2 (1.7%) resulted in death, 3 (2.5%) required hospitalization, and 1 (0.8%) were considered life-threatening.
Is Mitochondrial toxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ABACAVIR. However, 121 reports have been filed with the FAERS database.
What Other Side Effects Does ABACAVIR Cause?
Exposure during pregnancy (504)
Virologic failure (490)
Treatment failure (450)
Pyrexia (441)
Foetal exposure during pregnancy (418)
Viral mutation identified (378)
Pathogen resistance (367)
Rash (349)
Hypertension (336)
Hypersensitivity (329)
What Other Drugs Cause Mitochondrial toxicity?
LAMIVUDINE (188)
STAVUDINE (180)
ZIDOVUDINE (177)
DIDANOSINE (174)
NEVIRAPINE (174)
SAQUINAVIR (165)
TENOFOVIR DISOPROXIL (161)
INDINAVIR (156)
LOPINAVIR\RITONAVIR (151)
ENFUVIRTIDE (149)
Which ABACAVIR Alternatives Have Lower Mitochondrial toxicity Risk?
ABACAVIR vs ABACAVIR\DOLUTEGRAVIR\LAMIVUDINE
ABACAVIR vs ABACAVIR\LAMIVUDINE
ABACAVIR vs ABACAVIR\LAMIVUDINE\ZIDOVUDINE
ABACAVIR vs ABALOPARATIDE
ABACAVIR vs ABATACEPT