Does LAMIVUDINE Cause Mitochondrial toxicity? 188 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 188 reports of Mitochondrial toxicity have been filed in association with LAMIVUDINE (Lamivudine and Zidovudine). This represents 1.1% of all adverse event reports for LAMIVUDINE.
188
Reports of Mitochondrial toxicity with LAMIVUDINE
1.1%
of all LAMIVUDINE reports
3
Deaths
10
Hospitalizations
How Dangerous Is Mitochondrial toxicity From LAMIVUDINE?
Of the 188 reports, 3 (1.6%) resulted in death, 10 (5.3%) required hospitalization, and 2 (1.1%) were considered life-threatening.
Is Mitochondrial toxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LAMIVUDINE. However, 188 reports have been filed with the FAERS database.
What Other Side Effects Does LAMIVUDINE Cause?
Foetal exposure during pregnancy (1,905)
Virologic failure (1,894)
Drug resistance (1,889)
Pathogen resistance (1,733)
Viral mutation identified (1,631)
Treatment failure (933)
Exposure during pregnancy (846)
Drug interaction (744)
Drug ineffective (726)
Immune reconstitution inflammatory syndrome (625)
What Other Drugs Cause Mitochondrial toxicity?
STAVUDINE (180)
ZIDOVUDINE (177)
DIDANOSINE (174)
NEVIRAPINE (174)
SAQUINAVIR (165)
TENOFOVIR DISOPROXIL (161)
INDINAVIR (156)
LOPINAVIR\RITONAVIR (151)
ENFUVIRTIDE (149)
ABACAVIR (121)
Which LAMIVUDINE Alternatives Have Lower Mitochondrial toxicity Risk?
LAMIVUDINE vs LAMIVUDINE\NEVIRAPINE\ZIDOVUDINE
LAMIVUDINE vs LAMIVUDINE\TENOFOVIR
LAMIVUDINE vs LAMIVUDINE\TENOFOVIR DISOPROXIL
LAMIVUDINE vs LAMIVUDINE\ZIDOVUDINE
LAMIVUDINE vs LAMOTRIGINE