Does ACETAMINOPHEN Cause Hepatic failure? 1,392 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,392 reports of Hepatic failure have been filed in association with ACETAMINOPHEN (Hydrocodone Bitartrate and Acetaminophen). This represents 1.0% of all adverse event reports for ACETAMINOPHEN.
1,392
Reports of Hepatic failure with ACETAMINOPHEN
1.0%
of all ACETAMINOPHEN reports
554
Deaths
825
Hospitalizations
How Dangerous Is Hepatic failure From ACETAMINOPHEN?
Of the 1,392 reports, 554 (39.8%) resulted in death, 825 (59.3%) required hospitalization, and 301 (21.6%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ACETAMINOPHEN. However, 1,392 reports have been filed with the FAERS database.
What Other Side Effects Does ACETAMINOPHEN Cause?
Drug ineffective (17,522)
Toxicity to various agents (16,128)
Off label use (9,410)
Vomiting (9,055)
Pain (8,573)
Fatigue (8,202)
Overdose (7,917)
Nausea (7,245)
Rash (7,107)
Headache (7,084)
What Other Drugs Cause Hepatic failure?
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
NIVOLUMAB (382)
Which ACETAMINOPHEN Alternatives Have Lower Hepatic failure Risk?
ACETAMINOPHEN vs ACETAMINOPHEN AND OR DEXTROMETHORPHAN AND OR DIPHENHYDRAMINE AND OR GUAIFENESIN AND OR PHENYLEPHRINE AND OR PSEUDOEPHEDRINE
ACETAMINOPHEN vs ACETAMINOPHEN W/HYDROCODONE
ACETAMINOPHEN vs ACETAMINOPHEN\ASPIRIN\CAFFEINE
ACETAMINOPHEN vs ACETAMINOPHEN\ASPIRIN\CAFFEINE\SALICYLAMIDE
ACETAMINOPHEN vs ACETAMINOPHEN\BELLADONNA LEAF\CAFFEINE\OPIUM