Does SOFOSBUVIR Cause Hepatic failure? 525 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 525 reports of Hepatic failure have been filed in association with SOFOSBUVIR (Epclusa). This represents 3.0% of all adverse event reports for SOFOSBUVIR.
525
Reports of Hepatic failure with SOFOSBUVIR
3.0%
of all SOFOSBUVIR reports
178
Deaths
329
Hospitalizations
How Dangerous Is Hepatic failure From SOFOSBUVIR?
Of the 525 reports, 178 (33.9%) resulted in death, 329 (62.7%) required hospitalization, and 22 (4.2%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SOFOSBUVIR. However, 525 reports have been filed with the FAERS database.
What Other Side Effects Does SOFOSBUVIR Cause?
Fatigue (2,004)
Drug ineffective (1,833)
Hepatitis c (1,662)
Headache (1,417)
Nausea (1,211)
Off label use (1,184)
Anaemia (1,065)
Insomnia (940)
Hepatocellular carcinoma (877)
Treatment failure (806)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
NIVOLUMAB (382)
Which SOFOSBUVIR Alternatives Have Lower Hepatic failure Risk?
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR\VOXILAPREVIR
SOFOSBUVIR vs SOLIFENACIN
SOFOSBUVIR vs SOLIRIS
SOFOSBUVIR vs SOLOSTAR