ADAGRASIB for K-ras gene mutation: Side Effects & Safety Data
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There are 6 adverse event reports in the FDA FAERS database where ADAGRASIB was used for K-ras gene mutation.
Most Reported Side Effects for ADAGRASIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 272 | 30.3% | 258 | 21 |
| Diarrhoea | 113 | 12.6% | 9 | 46 |
| Hospitalisation | 108 | 12.0% | 7 | 108 |
| Nausea | 87 | 9.7% | 13 | 47 |
| Vomiting | 79 | 8.8% | 11 | 44 |
| Off label use | 70 | 7.8% | 12 | 27 |
| Asthenia | 61 | 6.8% | 10 | 39 |
| Fatigue | 51 | 5.7% | 4 | 21 |
| Decreased appetite | 43 | 4.8% | 4 | 20 |
| Dehydration | 35 | 3.9% | 3 | 25 |
| Dyspnoea | 32 | 3.6% | 7 | 18 |
| Dizziness | 27 | 3.0% | 3 | 16 |
| Acute kidney injury | 26 | 2.9% | 6 | 19 |
| Weight decreased | 24 | 2.7% | 7 | 12 |
| General physical health deterioration | 19 | 2.1% | 7 | 12 |
Other Indications for ADAGRASIB
Lung neoplasm malignant (388)
Product used for unknown indication (189)
Non-small cell lung cancer (92)
Lung adenocarcinoma (42)
Colon cancer (41)
Lung adenocarcinoma stage iv (20)
Non-small cell lung cancer metastatic (15)
Bronchial carcinoma (13)
Colorectal cancer (11)
Colorectal cancer metastatic (9)
Other Drugs Used for K-ras gene mutation
SOTORASIB (752)
AMG-510 (173)
IRINOTECAN (40)
PANITUMUMAB (36)
CETUXIMAB (29)
PEMBROLIZUMAB (28)
BEVACIZUMAB (19)
DALOTUZUMAB (18)
CARBOPLATIN (17)
FLUOROURACIL (17)