AMG-510 for K-ras gene mutation: Side Effects & Safety Data

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There are 173 adverse event reports in the FDA FAERS database where AMG-510 was used for K-ras gene mutation.

Most Reported Side Effects for AMG-510

Side Effect	Reports	%	Deaths	Hosp.
Non-small cell lung cancer	134	36.7%	56	22
Hepatic cytolysis	48	13.2%	1	9
Death	33	9.0%	33	3
Diarrhoea	31	8.5%	3	10
Cholestasis	17	4.7%	0	6
Dyspnoea	9	2.5%	4	8
Alanine aminotransferase increased	8	2.2%	2	4
Colitis	7	1.9%	0	7
Dehydration	7	1.9%	0	7
Drug-induced liver injury	7	1.9%	0	5
Respiratory failure	7	1.9%	7	5
General physical health deterioration	6	1.6%	4	0
Hypokalaemia	6	1.6%	1	5
Pulmonary embolism	6	1.6%	1	5
Fatigue	5	1.4%	0	1