SOTORASIB for K-ras gene mutation: Side Effects & Safety Data

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There are 752 adverse event reports in the FDA FAERS database where SOTORASIB was used for K-ras gene mutation.

Most Reported Side Effects for SOTORASIB

Side Effect	Reports	%	Deaths	Hosp.
Non-small cell lung cancer	483	16.5%	131	55
Death	319	10.9%	311	19
Disease progression	314	10.7%	83	9
Diarrhoea	284	9.7%	39	62
Off label use	193	6.6%	41	22
Nausea	98	3.4%	16	27
Non-small cell lung cancer metastatic	93	3.2%	33	16
Hepatotoxicity	91	3.1%	16	16
Fatigue	87	3.0%	5	14
Hepatic function abnormal	80	2.7%	12	27
Aspartate aminotransferase increased	71	2.4%	6	19
Alanine aminotransferase increased	70	2.4%	5	17
Lung neoplasm malignant	64	2.2%	17	8
Drug ineffective	62	2.1%	8	5
Decreased appetite	56	1.9%	11	16