Does AMG-510 Cause Cholestasis? 17 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 17 reports of Cholestasis have been filed in association with AMG-510. This represents 4.7% of all adverse event reports for AMG-510.
17
Reports of Cholestasis with AMG-510
4.7%
of all AMG-510 reports
0
Deaths
6
Hospitalizations
How Dangerous Is Cholestasis From AMG-510?
Of the 17 reports, 6 (35.3%) required hospitalization.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMG-510. However, 17 reports have been filed with the FAERS database.
What Other Side Effects Does AMG-510 Cause?
Non-small cell lung cancer (134)
Hepatic cytolysis (48)
Death (33)
Diarrhoea (31)
Dyspnoea (9)
Alanine aminotransferase increased (8)
Colitis (7)
Dehydration (7)
Drug-induced liver injury (7)
Respiratory failure (7)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which AMG-510 Alternatives Have Lower Cholestasis Risk?
AMG-510 vs AMIFAMPRIDINE
AMG-510 vs AMIFOSTINE
AMG-510 vs AMIKACIN
AMG-510 vs AMILORIDE
AMG-510 vs AMILORIDE\HYDROCHLOROTHIAZIDE