Does AMG-510 Cause Hepatic cytolysis? 48 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 48 reports of Hepatic cytolysis have been filed in association with AMG-510. This represents 13.2% of all adverse event reports for AMG-510.
48
Reports of Hepatic cytolysis with AMG-510
13.2%
of all AMG-510 reports
1
Deaths
9
Hospitalizations
How Dangerous Is Hepatic cytolysis From AMG-510?
Of the 48 reports, 1 (2.1%) resulted in death, 9 (18.8%) required hospitalization.
Is Hepatic cytolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMG-510. However, 48 reports have been filed with the FAERS database.
What Other Side Effects Does AMG-510 Cause?
Non-small cell lung cancer (134)
Death (33)
Diarrhoea (31)
Cholestasis (17)
Dyspnoea (9)
Alanine aminotransferase increased (8)
Colitis (7)
Dehydration (7)
Drug-induced liver injury (7)
Respiratory failure (7)
What Other Drugs Cause Hepatic cytolysis?
ACETAMINOPHEN (1,469)
ATORVASTATIN (681)
PEMBROLIZUMAB (601)
CARBOPLATIN (577)
METHOTREXATE (468)
SULFAMETHOXAZOLE\TRIMETHOPRIM (356)
PACLITAXEL (324)
ENOXAPARIN (307)
AMOXICILLIN (273)
VALACYCLOVIR (261)
Which AMG-510 Alternatives Have Lower Hepatic cytolysis Risk?
AMG-510 vs AMIFAMPRIDINE
AMG-510 vs AMIFOSTINE
AMG-510 vs AMIKACIN
AMG-510 vs AMILORIDE
AMG-510 vs AMILORIDE\HYDROCHLOROTHIAZIDE