Does ACETAMINOPHEN Cause Hepatic cytolysis? 1,469 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,469 reports of Hepatic cytolysis have been filed in association with ACETAMINOPHEN (Hydrocodone Bitartrate and Acetaminophen). This represents 1.1% of all adverse event reports for ACETAMINOPHEN.
1,469
Reports of Hepatic cytolysis with ACETAMINOPHEN
1.1%
of all ACETAMINOPHEN reports
37
Deaths
1,019
Hospitalizations
How Dangerous Is Hepatic cytolysis From ACETAMINOPHEN?
Of the 1,469 reports, 37 (2.5%) resulted in death, 1,019 (69.4%) required hospitalization, and 122 (8.3%) were considered life-threatening.
Is Hepatic cytolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ACETAMINOPHEN. However, 1,469 reports have been filed with the FAERS database.
What Other Side Effects Does ACETAMINOPHEN Cause?
Drug ineffective (17,522)
Toxicity to various agents (16,128)
Off label use (9,410)
Vomiting (9,055)
Pain (8,573)
Fatigue (8,202)
Overdose (7,917)
Nausea (7,245)
Rash (7,107)
Headache (7,084)
What Other Drugs Cause Hepatic cytolysis?
ATORVASTATIN (681)
PEMBROLIZUMAB (601)
CARBOPLATIN (577)
METHOTREXATE (468)
SULFAMETHOXAZOLE\TRIMETHOPRIM (356)
PACLITAXEL (324)
ENOXAPARIN (307)
AMOXICILLIN (273)
VALACYCLOVIR (261)
PEMETREXED (252)
Which ACETAMINOPHEN Alternatives Have Lower Hepatic cytolysis Risk?
ACETAMINOPHEN vs ACETAMINOPHEN AND OR DEXTROMETHORPHAN AND OR DIPHENHYDRAMINE AND OR GUAIFENESIN AND OR PHENYLEPHRINE AND OR PSEUDOEPHEDRINE
ACETAMINOPHEN vs ACETAMINOPHEN W/HYDROCODONE
ACETAMINOPHEN vs ACETAMINOPHEN\ASPIRIN\CAFFEINE
ACETAMINOPHEN vs ACETAMINOPHEN\ASPIRIN\CAFFEINE\SALICYLAMIDE
ACETAMINOPHEN vs ACETAMINOPHEN\BELLADONNA LEAF\CAFFEINE\OPIUM