Does PACLITAXEL Cause Hepatic cytolysis? 324 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 324 reports of Hepatic cytolysis have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.4% of all adverse event reports for PACLITAXEL.
324
Reports of Hepatic cytolysis with PACLITAXEL
0.4%
of all PACLITAXEL reports
21
Deaths
155
Hospitalizations
How Dangerous Is Hepatic cytolysis From PACLITAXEL?
Of the 324 reports, 21 (6.5%) resulted in death, 155 (47.8%) required hospitalization, and 11 (3.4%) were considered life-threatening.
Is Hepatic cytolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 324 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Hepatic cytolysis?
ACETAMINOPHEN (1,469)
ATORVASTATIN (681)
PEMBROLIZUMAB (601)
CARBOPLATIN (577)
METHOTREXATE (468)
SULFAMETHOXAZOLE\TRIMETHOPRIM (356)
ENOXAPARIN (307)
AMOXICILLIN (273)
VALACYCLOVIR (261)
PEMETREXED (252)
Which PACLITAXEL Alternatives Have Lower Hepatic cytolysis Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON