Does PEMETREXED Cause Hepatic cytolysis? 252 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 252 reports of Hepatic cytolysis have been filed in association with PEMETREXED (Pemetrexed). This represents 1.1% of all adverse event reports for PEMETREXED.
252
Reports of Hepatic cytolysis with PEMETREXED
1.1%
of all PEMETREXED reports
16
Deaths
119
Hospitalizations
How Dangerous Is Hepatic cytolysis From PEMETREXED?
Of the 252 reports, 16 (6.3%) resulted in death, 119 (47.2%) required hospitalization, and 4 (1.6%) were considered life-threatening.
Is Hepatic cytolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMETREXED. However, 252 reports have been filed with the FAERS database.
What Other Side Effects Does PEMETREXED Cause?
Malignant neoplasm progression (2,149)
Off label use (1,663)
Anaemia (1,430)
Pancytopenia (1,236)
Neutropenia (1,200)
Nausea (1,195)
Diarrhoea (1,165)
Acute kidney injury (1,105)
Thrombocytopenia (1,059)
Disease progression (969)
What Other Drugs Cause Hepatic cytolysis?
ACETAMINOPHEN (1,469)
ATORVASTATIN (681)
PEMBROLIZUMAB (601)
CARBOPLATIN (577)
METHOTREXATE (468)
SULFAMETHOXAZOLE\TRIMETHOPRIM (356)
PACLITAXEL (324)
ENOXAPARIN (307)
AMOXICILLIN (273)
VALACYCLOVIR (261)
Which PEMETREXED Alternatives Have Lower Hepatic cytolysis Risk?
PEMETREXED vs PEMIGATINIB
PEMETREXED vs PENICILLAMINE
PEMETREXED vs PENICILLIN
PEMETREXED vs PENICILLIN G
PEMETREXED vs PENICILLIN G BENZATHINE