AFATINIB for Neoplasm malignant: Side Effects & Safety Data
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There are 49 adverse event reports in the FDA FAERS database where AFATINIB was used for Neoplasm malignant.
Most Reported Side Effects for AFATINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 2,001 | 32.9% | 351 | 984 |
| Malignant neoplasm progression | 1,622 | 26.7% | 445 | 283 |
| Rash | 808 | 13.3% | 131 | 315 |
| Stomatitis | 468 | 7.7% | 77 | 234 |
| Death | 443 | 7.3% | 443 | 63 |
| Nausea | 430 | 7.1% | 69 | 280 |
| Decreased appetite | 412 | 6.8% | 85 | 255 |
| Vomiting | 381 | 6.3% | 67 | 271 |
| Paronychia | 344 | 5.7% | 62 | 133 |
| Dehydration | 323 | 5.3% | 56 | 276 |
| Fatigue | 256 | 4.2% | 52 | 128 |
| Metastases to central nervous system | 248 | 4.1% | 72 | 58 |
| Asthenia | 221 | 3.6% | 46 | 151 |
| Off label use | 204 | 3.4% | 64 | 37 |
| Drug ineffective | 203 | 3.3% | 31 | 47 |
Other Indications for AFATINIB
Non-small cell lung cancer (2,010)
Product used for unknown indication (916)
Lung adenocarcinoma (876)
Lung neoplasm malignant (824)
Egfr gene mutation (780)
Non-small cell lung cancer metastatic (285)
Lung adenocarcinoma stage iv (146)
Adenocarcinoma (144)
Squamous cell carcinoma of head and neck (76)
Non-small cell lung cancer stage iv (74)
Other Drugs Used for Neoplasm malignant
PALBOCICLIB (1,996)
CAPECITABINE (1,493)
PEMBROLIZUMAB (1,135)
PACLITAXEL (984)
CARBOPLATIN (977)
NIVOLUMAB (947)
OXALIPLATIN (823)
PAZOPANIB (716)
CYCLOPHOSPHAMIDE (685)
FLUOROURACIL (676)