Does AFATINIB Cause Bone marrow failure? 9 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 9 reports of Bone marrow failure have been filed in association with AFATINIB (Gilotrif). This represents 0.2% of all adverse event reports for AFATINIB.
9
Reports of Bone marrow failure with AFATINIB
0.2%
of all AFATINIB reports
3
Deaths
4
Hospitalizations
How Dangerous Is Bone marrow failure From AFATINIB?
Of the 9 reports, 3 (33.3%) resulted in death, 4 (44.4%) required hospitalization.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AFATINIB. However, 9 reports have been filed with the FAERS database.
What Other Side Effects Does AFATINIB Cause?
Diarrhoea (2,001)
Malignant neoplasm progression (1,622)
Rash (808)
Stomatitis (468)
Death (443)
Nausea (430)
Decreased appetite (412)
Vomiting (381)
Paronychia (344)
Dehydration (323)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which AFATINIB Alternatives Have Lower Bone marrow failure Risk?
AFATINIB vs AFINITOR
AFATINIB vs AFLIBERCEPT
AFATINIB vs AGALSIDASE ALFA
AFATINIB vs AGALSIDASE BETA
AFATINIB vs AGOMELATINE