Bone marrow failure: Which Medications Cause It? (14,526 Reports Across 504 Drugs)
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Bone marrow failure has been reported as an adverse event with 504 different drugs in the FDA's FAERS database, with 14,526 total reports. 2,673 of these reports resulted in death.The drugs most commonly associated with Bone marrow failure are CYCLOPHOSPHAMIDE, METHOTREXATE, and ETOPOSIDE.
14,526
Total Reports
504
Drugs Involved
2,673
Deaths
5,332
Hospitalizations
53.8 yrs
Average Patient Age
54.7% / 45.3%
Female / Male
Which Drugs Cause Bone marrow failure Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| CYCLOPHOSPHAMIDE | 1,834 | 1.4% | 332 | 655 | 200 |
| METHOTREXATE | 1,401 | 0.6% | 374 | 783 | 254 |
| ETOPOSIDE | 1,081 | 2.1% | 265 | 390 | 167 |
| RITUXIMAB | 1,060 | 0.6% | 168 | 339 | 97 |
| CYTARABINE | 1,052 | 2.4% | 251 | 384 | 163 |
| VINCRISTINE | 1,001 | 1.4% | 237 | 357 | 155 |
| DOXORUBICIN | 1,000 | 1.2% | 234 | 357 | 144 |
| PALBOCICLIB | 951 | 1.0% | 24 | 111 | 8 |