Does FLUOROURACIL Cause Bone marrow failure? 487 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 487 reports of Bone marrow failure have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.9% of all adverse event reports for FLUOROURACIL.
487
Reports of Bone marrow failure with FLUOROURACIL
0.9%
of all FLUOROURACIL reports
76
Deaths
141
Hospitalizations
How Dangerous Is Bone marrow failure From FLUOROURACIL?
Of the 487 reports, 76 (15.6%) resulted in death, 141 (29.0%) required hospitalization, and 61 (12.5%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 487 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which FLUOROURACIL Alternatives Have Lower Bone marrow failure Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE