Does AFATINIB Cause Clostridium difficile infection? 19 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 19 reports of Clostridium difficile infection have been filed in association with AFATINIB (Gilotrif). This represents 0.3% of all adverse event reports for AFATINIB.
19
Reports of Clostridium difficile infection with AFATINIB
0.3%
of all AFATINIB reports
2
Deaths
16
Hospitalizations
How Dangerous Is Clostridium difficile infection From AFATINIB?
Of the 19 reports, 2 (10.5%) resulted in death, 16 (84.2%) required hospitalization, and 1 (5.3%) were considered life-threatening.
Is Clostridium difficile infection Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AFATINIB. However, 19 reports have been filed with the FAERS database.
What Other Side Effects Does AFATINIB Cause?
Diarrhoea (2,001)
Malignant neoplasm progression (1,622)
Rash (808)
Stomatitis (468)
Death (443)
Nausea (430)
Decreased appetite (412)
Vomiting (381)
Paronychia (344)
Dehydration (323)
What Other Drugs Cause Clostridium difficile infection?
ADALIMUMAB (1,502)
INFLIXIMAB (1,419)
VEDOLIZUMAB (1,130)
LENALIDOMIDE (814)
VANCOMYCIN (743)
METRONIDAZOLE (619)
PREDNISONE (618)
METHOTREXATE (588)
RITUXIMAB (532)
CIPROFLOXACIN (508)
Which AFATINIB Alternatives Have Lower Clostridium difficile infection Risk?
AFATINIB vs AFINITOR
AFATINIB vs AFLIBERCEPT
AFATINIB vs AGALSIDASE ALFA
AFATINIB vs AGALSIDASE BETA
AFATINIB vs AGOMELATINE