Clostridium difficile infection: Which Medications Cause It? (18,915 Reports Across 613 Drugs)
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Clostridium difficile infection has been reported as an adverse event with 613 different drugs in the FDA's FAERS database, with 18,915 total reports. 1,490 of these reports resulted in death.The drugs most commonly associated with Clostridium difficile infection are ADALIMUMAB, INFLIXIMAB, and VEDOLIZUMAB.
18,915
Total Reports
613
Drugs Involved
1,490
Deaths
11,496
Hospitalizations
55.2 yrs
Average Patient Age
61.8% / 38.2%
Female / Male
Which Drugs Cause Clostridium difficile infection Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ADALIMUMAB | 1,502 | 0.3% | 33 | 977 | 21 |
| INFLIXIMAB | 1,419 | 1.0% | 27 | 686 | 8 |
| VEDOLIZUMAB | 1,130 | 1.5% | 12 | 588 | 11 |
| LENALIDOMIDE | 814 | 0.2% | 26 | 490 | 14 |
| VANCOMYCIN | 743 | 2.2% | 107 | 401 | 59 |
| METRONIDAZOLE | 619 | 2.7% | 76 | 331 | 57 |
| PREDNISONE | 618 | 0.4% | 55 | 456 | 38 |
| METHOTREXATE | 588 | 0.2% | 60 | 354 | 42 |
| RITUXIMAB | 532 | 0.3% | 48 | 311 | 79 |
| CIPROFLOXACIN | 508 | 1.2% | 63 | 308 | 53 |
| CYCLOPHOSPHAMIDE | 504 | 0.4% | 85 | 313 | 110 |
| USTEKINUMAB | 440 | 0.5% | 3 | 174 | 3 |
| CLINDAMYCIN | 368 | 2.2% | 9 | 147 | 27 |
| CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM | 366 | 0.4% | 67 | 336 | 2 |
| INFLIXIMAB-DYYB | 366 | 1.4% | 8 | 198 | 2 |
| TACROLIMUS | 363 | 0.4% | 51 | 219 | 37 |
| PANTOPRAZOLE | 331 | 0.4% | 46 | 204 | 17 |
| VINCRISTINE | 329 | 0.5% | 38 | 224 | 34 |
| PIPERACILLIN\TAZOBACTAM | 325 | 1.7% | 91 | 220 | 39 |
| DEXAMETHASONE | 313 | 0.3% | 58 | 219 | 47 |