Does AFATINIB Cause Constipation? 97 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 97 reports of Constipation have been filed in association with AFATINIB (Gilotrif). This represents 1.6% of all adverse event reports for AFATINIB.
97
Reports of Constipation with AFATINIB
1.6%
of all AFATINIB reports
20
Deaths
57
Hospitalizations
How Dangerous Is Constipation From AFATINIB?
Of the 97 reports, 20 (20.6%) resulted in death, 57 (58.8%) required hospitalization, and 2 (2.1%) were considered life-threatening.
Is Constipation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AFATINIB. However, 97 reports have been filed with the FAERS database.
What Other Side Effects Does AFATINIB Cause?
Diarrhoea (2,001)
Malignant neoplasm progression (1,622)
Rash (808)
Stomatitis (468)
Death (443)
Nausea (430)
Decreased appetite (412)
Vomiting (381)
Paronychia (344)
Dehydration (323)
What Other Drugs Cause Constipation?
LENALIDOMIDE (9,635)
NIRAPARIB (4,128)
ADALIMUMAB (4,063)
SEMAGLUTIDE (4,036)
TIRZEPATIDE (3,417)
ERENUMAB-AOOE (3,104)
MORPHINE (2,979)
OXYCODONE (2,747)
PALBOCICLIB (2,705)
POMALIDOMIDE (2,374)
Which AFATINIB Alternatives Have Lower Constipation Risk?
AFATINIB vs AFINITOR
AFATINIB vs AFLIBERCEPT
AFATINIB vs AGALSIDASE ALFA
AFATINIB vs AGALSIDASE BETA
AFATINIB vs AGOMELATINE