Does AFATINIB Cause Drug resistance? 106 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 106 reports of Drug resistance have been filed in association with AFATINIB (Gilotrif). This represents 1.7% of all adverse event reports for AFATINIB.
106
Reports of Drug resistance with AFATINIB
1.7%
of all AFATINIB reports
11
Deaths
9
Hospitalizations
How Dangerous Is Drug resistance From AFATINIB?
Of the 106 reports, 11 (10.4%) resulted in death, 9 (8.5%) required hospitalization.
Is Drug resistance Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AFATINIB. However, 106 reports have been filed with the FAERS database.
What Other Side Effects Does AFATINIB Cause?
Diarrhoea (2,001)
Malignant neoplasm progression (1,622)
Rash (808)
Stomatitis (468)
Death (443)
Nausea (430)
Decreased appetite (412)
Vomiting (381)
Paronychia (344)
Dehydration (323)
What Other Drugs Cause Drug resistance?
LAMIVUDINE (1,889)
IMATINIB (1,293)
GEFITINIB (1,228)
OSIMERTINIB (1,026)
NEVIRAPINE (862)
PREDNISONE (833)
CYCLOPHOSPHAMIDE (817)
LEVETIRACETAM (798)
METHOTREXATE (765)
TENOFOVIR DISOPROXIL (740)
Which AFATINIB Alternatives Have Lower Drug resistance Risk?
AFATINIB vs AFINITOR
AFATINIB vs AFLIBERCEPT
AFATINIB vs AGALSIDASE ALFA
AFATINIB vs AGALSIDASE BETA
AFATINIB vs AGOMELATINE