Does METHOTREXATE Cause Drug resistance? 765 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 765 reports of Drug resistance have been filed in association with METHOTREXATE (Methotrexate). This represents 0.3% of all adverse event reports for METHOTREXATE.
765
Reports of Drug resistance with METHOTREXATE
0.3%
of all METHOTREXATE reports
98
Deaths
158
Hospitalizations
How Dangerous Is Drug resistance From METHOTREXATE?
Of the 765 reports, 98 (12.8%) resulted in death, 158 (20.7%) required hospitalization, and 40 (5.2%) were considered life-threatening.
Is Drug resistance Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 765 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Drug resistance?
LAMIVUDINE (1,889)
IMATINIB (1,293)
GEFITINIB (1,228)
OSIMERTINIB (1,026)
NEVIRAPINE (862)
PREDNISONE (833)
CYCLOPHOSPHAMIDE (817)
LEVETIRACETAM (798)
TENOFOVIR DISOPROXIL (740)
RITUXIMAB (732)
Which METHOTREXATE Alternatives Have Lower Drug resistance Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA