Drug resistance: Which Medications Cause It? (22,006 Reports Across 834 Drugs)
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Drug resistance has been reported as an adverse event with 834 different drugs in the FDA's FAERS database, with 22,006 total reports. 2,415 of these reports resulted in death.The drugs most commonly associated with Drug resistance are LAMIVUDINE, IMATINIB, and GEFITINIB.
22,006
Total Reports
834
Drugs Involved
2,415
Deaths
4,124
Hospitalizations
48.1 yrs
Average Patient Age
48.7% / 51.3%
Female / Male
Which Drugs Cause Drug resistance Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| LAMIVUDINE | 1,889 | 11.3% | 73 | 220 | 7 |
| IMATINIB | 1,293 | 3.0% | 220 | 142 | 35 |
| GEFITINIB | 1,228 | 26.1% | 95 | 115 | 4 |
| OSIMERTINIB | 1,026 | 3.7% | 139 | 98 | 9 |
| NEVIRAPINE | 862 | 13.0% | 33 | 14 | 2 |
| PREDNISONE | 833 | 0.5% | 104 | 236 | 65 |
| CYCLOPHOSPHAMIDE | 817 | 0.6% | 198 | 188 | 91 |
| LEVETIRACETAM | 798 | 1.3% | 17 | 165 | 39 |
| METHOTREXATE | 765 | 0.3% | 98 | 158 | 40 |
| TENOFOVIR DISOPROXIL | 740 | 2.7% | 32 | 114 | 3 |
| RITUXIMAB | 732 | 0.4% | 84 | 160 | 71 |
| EFAVIRENZ | 654 | 8.3% | 15 | 40 | 0 |
| MYCOPHENOLATE MOFETIL | 606 | 0.8% | 77 | 145 | 10 |
| GANCICLOVIR | 594 | 11.9% | 97 | 127 | 29 |
| TACROLIMUS | 585 | 0.6% | 81 | 191 | 10 |
| LINEZOLID | 580 | 3.2% | 74 | 145 | 36 |
| PREDNISOLONE | 577 | 0.7% | 68 | 159 | 25 |
| ZIDOVUDINE | 568 | 8.5% | 32 | 29 | 2 |
| CYCLOSPORINE | 563 | 0.8% | 100 | 167 | 21 |
| ADALIMUMAB | 539 | 0.1% | 10 | 102 | 4 |