Does AFATINIB Cause Pruritus? 157 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 157 reports of Pruritus have been filed in association with AFATINIB (Gilotrif). This represents 2.6% of all adverse event reports for AFATINIB.
157
Reports of Pruritus with AFATINIB
2.6%
of all AFATINIB reports
15
Deaths
58
Hospitalizations
How Dangerous Is Pruritus From AFATINIB?
Of the 157 reports, 15 (9.6%) resulted in death, 58 (36.9%) required hospitalization, and 5 (3.2%) were considered life-threatening.
Is Pruritus Listed in the Official Label?
Yes, Pruritus is listed as a known adverse reaction in the official FDA drug label for AFATINIB.
What Other Side Effects Does AFATINIB Cause?
Diarrhoea (2,001)
Malignant neoplasm progression (1,622)
Rash (808)
Stomatitis (468)
Death (443)
Nausea (430)
Decreased appetite (412)
Vomiting (381)
Paronychia (344)
Dehydration (323)
What Other Drugs Cause Pruritus?
DUPILUMAB (44,279)
ADAPALENE (12,072)
ADALIMUMAB (9,644)
AVOBENZONE\OCTISALATE\OCTOCRYLENE (9,439)
SECUKINUMAB (8,755)
ETANERCEPT (8,047)
METHOTREXATE (7,526)
LENALIDOMIDE (6,304)
TOCILIZUMAB (5,973)
RITUXIMAB (5,548)
Which AFATINIB Alternatives Have Lower Pruritus Risk?
AFATINIB vs AFINITOR
AFATINIB vs AFLIBERCEPT
AFATINIB vs AGALSIDASE ALFA
AFATINIB vs AGALSIDASE BETA
AFATINIB vs AGOMELATINE