Does ALLOPURINOL Cause Angioedema? 184 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 184 reports of Angioedema have been filed in association with ALLOPURINOL (Allopurinol). This represents 1.0% of all adverse event reports for ALLOPURINOL.
184
Reports of Angioedema with ALLOPURINOL
1.0%
of all ALLOPURINOL reports
17
Deaths
87
Hospitalizations
How Dangerous Is Angioedema From ALLOPURINOL?
Of the 184 reports, 17 (9.2%) resulted in death, 87 (47.3%) required hospitalization, and 21 (11.4%) were considered life-threatening.
Is Angioedema Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 184 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Angioedema?
LISINOPRIL (5,370)
IBUPROFEN (2,507)
OMALIZUMAB (1,650)
ACETAMINOPHEN (1,152)
RAMIPRIL (1,130)
AMOXICILLIN (943)
ASPIRIN (820)
CETIRIZINE (766)
DICLOFENAC (766)
SACUBITRIL\VALSARTAN (730)
Which ALLOPURINOL Alternatives Have Lower Angioedema Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN