Angioedema: Which Medications Cause It? (31,527 Reports Across 931 Drugs)
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Angioedema has been reported as an adverse event with 931 different drugs in the FDA's FAERS database, with 31,527 total reports. 497 of these reports resulted in death.The drugs most commonly associated with Angioedema are LISINOPRIL, IBUPROFEN, and OMALIZUMAB.
31,527
Total Reports
931
Drugs Involved
497
Deaths
11,161
Hospitalizations
53.3 yrs
Average Patient Age
53.1% / 46.9%
Female / Male
Which Drugs Cause Angioedema Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| LISINOPRIL | 5,370 | 14.6% | 106 | 3,455 | 1,314 |
| IBUPROFEN | 2,507 | 2.9% | 5 | 310 | 150 |
| OMALIZUMAB | 1,650 | 2.6% | 3 | 409 | 83 |
| ACETAMINOPHEN | 1,152 | 0.8% | 25 | 176 | 126 |
| RAMIPRIL | 1,130 | 3.4% | 76 | 657 | 356 |
| AMOXICILLIN | 943 | 3.1% | 5 | 199 | 65 |
| ASPIRIN | 820 | 0.9% | 26 | 160 | 84 |
| CETIRIZINE | 766 | 1.6% | 5 | 177 | 137 |
| DICLOFENAC | 766 | 0.9% | 1 | 123 | 64 |
| SACUBITRIL\VALSARTAN | 730 | 0.7% | 28 | 170 | 52 |
| NAPROXEN | 719 | 1.4% | 0 | 179 | 138 |
| LANSOPRAZOLE | 703 | 1.2% | 8 | 207 | 115 |
| ESOMEPRAZOLE | 622 | 0.8% | 0 | 149 | 111 |
| ALTEPLASE | 603 | 4.8% | 37 | 192 | 169 |
| AMLODIPINE | 562 | 0.9% | 25 | 295 | 100 |
| LEVOTHYROXINE | 513 | 0.8% | 0 | 147 | 101 |
| HYDROCHLOROTHIAZIDE | 480 | 2.3% | 0 | 167 | 108 |
| APIXABAN | 471 | 0.3% | 0 | 135 | 110 |
| HYDROCHLOROTHIAZIDE\LISINOPRIL | 463 | 17.6% | 9 | 312 | 112 |
| SIMVASTATIN | 451 | 1.7% | 18 | 141 | 127 |