Does ALLOPURINOL Cause Appendicitis? 264 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 264 reports of Appendicitis have been filed in association with ALLOPURINOL (Allopurinol). This represents 1.4% of all adverse event reports for ALLOPURINOL.
264
Reports of Appendicitis with ALLOPURINOL
1.4%
of all ALLOPURINOL reports
262
Deaths
135
Hospitalizations
How Dangerous Is Appendicitis From ALLOPURINOL?
Of the 264 reports, 262 (99.2%) resulted in death, 135 (51.1%) required hospitalization, and 116 (43.9%) were considered life-threatening.
Is Appendicitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 264 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Appendicitis?
ADALIMUMAB (372)
METRONIDAZOLE (291)
GABAPENTIN (281)
ONDANSETRON (278)
SIMVASTATIN (270)
CEFTRIAXONE (268)
HYDROMORPHONE (265)
ALBUTEROL (264)
LANSOPRAZOLE (263)
ACETAMINOPHEN (260)
Which ALLOPURINOL Alternatives Have Lower Appendicitis Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN