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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Appendicitis: Which Medications Cause It? (6,639 Reports Across 547 Drugs)

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Appendicitis has been reported as an adverse event with 547 different drugs in the FDA's FAERS database, with 6,639 total reports. 496 of these reports resulted in death.The drugs most commonly associated with Appendicitis are ADALIMUMAB, METRONIDAZOLE, and GABAPENTIN.

6,639
Total Reports
547
Drugs Involved
496
Deaths
4,615
Hospitalizations
48.2 yrs
Average Patient Age
53.6% / 46.4%
Female / Male

Which Drugs Cause Appendicitis Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
ADALIMUMAB 372 0.1% 4 254 5
METRONIDAZOLE 291 1.3% 265 154 114
GABAPENTIN 281 0.4% 255 153 126
ONDANSETRON 278 1.2% 262 140 121
SIMVASTATIN 270 1.0% 256 145 118
CEFTRIAXONE 268 1.4% 260 137 114
HYDROMORPHONE 265 0.3% 258 136 117
ALBUTEROL 264 0.3% 257 139 119
ALLOPURINOL 264 1.4% 262 135 116
LANSOPRAZOLE 263 0.4% 262 137 124
ACETAMINOPHEN 260 0.2% 256 133 115
AMIODARONE 253 1.0% 252 127 111
DOBUTAMINE 252 15.4% 252 126 113
HEPARIN 249 1.4% 248 131 108
PHYTONADIONE 243 19.1% 243 120 106
WARFARIN 243 0.6% 239 118 102
IPRATROPIUM 241 3.2% 241 125 111
DARBEPOETIN ALFA 240 0.7% 233 116 96
INSULIN ASPART 239 1.1% 232 119 101
MELATONIN 238 5.8% 237 112 98

View all 547 drugs →

Top 3 Drugs Associated With Appendicitis

372 reports
291 reports
281 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)