Does ALLOPURINOL Cause Cardiac failure? 378 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 378 reports of Cardiac failure have been filed in association with ALLOPURINOL (Allopurinol). This represents 2.0% of all adverse event reports for ALLOPURINOL.
378
Reports of Cardiac failure with ALLOPURINOL
2.0%
of all ALLOPURINOL reports
92
Deaths
312
Hospitalizations
How Dangerous Is Cardiac failure From ALLOPURINOL?
Of the 378 reports, 92 (24.3%) resulted in death, 312 (82.5%) required hospitalization, and 37 (9.8%) were considered life-threatening.
Is Cardiac failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 378 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Cardiac failure?
SACUBITRIL\VALSARTAN (4,504)
FUROSEMIDE (1,841)
APIXABAN (1,575)
CYCLOPHOSPHAMIDE (1,514)
DOXORUBICIN (1,367)
ADALIMUMAB (1,278)
DEXAMETHASONE (1,271)
TREPROSTINIL (1,168)
BISOPROLOL (1,159)
LENALIDOMIDE (1,115)
Which ALLOPURINOL Alternatives Have Lower Cardiac failure Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN