Does ALLOPURINOL Cause Dry eye? 49 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 49 reports of Dry eye have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.3% of all adverse event reports for ALLOPURINOL.
49
Reports of Dry eye with ALLOPURINOL
0.3%
of all ALLOPURINOL reports
13
Deaths
25
Hospitalizations
How Dangerous Is Dry eye From ALLOPURINOL?
Of the 49 reports, 13 (26.5%) resulted in death, 25 (51.0%) required hospitalization, and 15 (30.6%) were considered life-threatening.
Is Dry eye Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 49 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Dry eye?
DUPILUMAB (10,892)
CYCLOSPORINE (1,310)
ADALIMUMAB (1,253)
METHOTREXATE (1,023)
LIFITEGRAST (1,013)
ETANERCEPT (992)
TOFACITINIB (756)
LENALIDOMIDE (649)
TOCILIZUMAB (565)
CENEGERMIN-BKBJ (537)
Which ALLOPURINOL Alternatives Have Lower Dry eye Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN