Does METHOTREXATE Cause Dry eye? 1,023 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,023 reports of Dry eye have been filed in association with METHOTREXATE (Methotrexate). This represents 0.4% of all adverse event reports for METHOTREXATE.
1,023
Reports of Dry eye with METHOTREXATE
0.4%
of all METHOTREXATE reports
18
Deaths
308
Hospitalizations
How Dangerous Is Dry eye From METHOTREXATE?
Of the 1,023 reports, 18 (1.8%) resulted in death, 308 (30.1%) required hospitalization, and 35 (3.4%) were considered life-threatening.
Is Dry eye Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 1,023 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Dry eye?
DUPILUMAB (10,892)
CYCLOSPORINE (1,310)
ADALIMUMAB (1,253)
LIFITEGRAST (1,013)
ETANERCEPT (992)
TOFACITINIB (756)
LENALIDOMIDE (649)
TOCILIZUMAB (565)
CENEGERMIN-BKBJ (537)
HYPROMELLOSE 2910 (521)
Which METHOTREXATE Alternatives Have Lower Dry eye Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA