Does ALLOPURINOL Cause Gastrointestinal toxicity? 20 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 20 reports of Gastrointestinal toxicity have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.1% of all adverse event reports for ALLOPURINOL.
20
Reports of Gastrointestinal toxicity with ALLOPURINOL
0.1%
of all ALLOPURINOL reports
13
Deaths
18
Hospitalizations
How Dangerous Is Gastrointestinal toxicity From ALLOPURINOL?
Of the 20 reports, 13 (65.0%) resulted in death, 18 (90.0%) required hospitalization, and 13 (65.0%) were considered life-threatening.
Is Gastrointestinal toxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 20 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Gastrointestinal toxicity?
CAPECITABINE (368)
FLUOROURACIL (358)
METHOTREXATE (345)
OXALIPLATIN (314)
CYCLOPHOSPHAMIDE (266)
RITUXIMAB (262)
CISPLATIN (251)
DOXORUBICIN (242)
IRINOTECAN (232)
CARBOPLATIN (231)
Which ALLOPURINOL Alternatives Have Lower Gastrointestinal toxicity Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN