Does ALLOPURINOL Cause Hyperleukocytosis? 7 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 7 reports of Hyperleukocytosis have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.0% of all adverse event reports for ALLOPURINOL.
7
Reports of Hyperleukocytosis with ALLOPURINOL
0.0%
of all ALLOPURINOL reports
1
Deaths
2
Hospitalizations
How Dangerous Is Hyperleukocytosis From ALLOPURINOL?
Of the 7 reports, 1 (14.3%) resulted in death, 2 (28.6%) required hospitalization.
Is Hyperleukocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 7 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Hyperleukocytosis?
CYCLOPHOSPHAMIDE (55)
PREDNISONE (54)
TRETINOIN (52)
ARSENIC TRIOXIDE (49)
RITUXIMAB (49)
ACETAMINOPHEN (44)
VINCRISTINE (44)
DEXAMETHASONE (42)
PANTOPRAZOLE (38)
AMOXICILLIN (36)
Which ALLOPURINOL Alternatives Have Lower Hyperleukocytosis Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN