Does ALLOPURINOL Cause Hyperpyrexia? 31 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 31 reports of Hyperpyrexia have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.2% of all adverse event reports for ALLOPURINOL.
31
Reports of Hyperpyrexia with ALLOPURINOL
0.2%
of all ALLOPURINOL reports
0
Deaths
28
Hospitalizations
How Dangerous Is Hyperpyrexia From ALLOPURINOL?
Of the 31 reports, 28 (90.3%) required hospitalization, and 3 (9.7%) were considered life-threatening.
Is Hyperpyrexia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 31 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Hyperpyrexia?
TRASTUZUMAB (146)
RITUXIMAB (139)
CYCLOPHOSPHAMIDE (133)
PACLITAXEL (100)
ZOLEDRONIC ACID (96)
OXALIPLATIN (94)
CARBOPLATIN (73)
GEMCITABINE (72)
VINCRISTINE (69)
DABRAFENIB (68)
Which ALLOPURINOL Alternatives Have Lower Hyperpyrexia Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN