Does ALLOPURINOL Cause Hyperthermia? 62 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 62 reports of Hyperthermia have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.3% of all adverse event reports for ALLOPURINOL.
62
Reports of Hyperthermia with ALLOPURINOL
0.3%
of all ALLOPURINOL reports
5
Deaths
50
Hospitalizations
How Dangerous Is Hyperthermia From ALLOPURINOL?
Of the 62 reports, 5 (8.1%) resulted in death, 50 (80.6%) required hospitalization, and 11 (17.7%) were considered life-threatening.
Is Hyperthermia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 62 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Hyperthermia?
QUETIAPINE (265)
OLANZAPINE (210)
ACETAMINOPHEN (196)
OXALIPLATIN (195)
RISPERIDONE (166)
LAMOTRIGINE (156)
HALOPERIDOL (138)
CARBOPLATIN (129)
FLUOROURACIL (115)
SERTRALINE (109)
Which ALLOPURINOL Alternatives Have Lower Hyperthermia Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN