Does ALLOPURINOL Cause Lactic acidosis? 219 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 219 reports of Lactic acidosis have been filed in association with ALLOPURINOL (Allopurinol). This represents 1.2% of all adverse event reports for ALLOPURINOL.
219
Reports of Lactic acidosis with ALLOPURINOL
1.2%
of all ALLOPURINOL reports
71
Deaths
98
Hospitalizations
How Dangerous Is Lactic acidosis From ALLOPURINOL?
Of the 219 reports, 71 (32.4%) resulted in death, 98 (44.7%) required hospitalization, and 79 (36.1%) were considered life-threatening.
Is Lactic acidosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 219 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Lactic acidosis?
METFORMIN (16,316)
AMLODIPINE (886)
LINEZOLID (824)
FUROSEMIDE (698)
ACETAMINOPHEN (561)
METFORMIN\SITAGLIPTIN (557)
ALBUTEROL (467)
EMPAGLIFLOZIN (434)
RAMIPRIL (430)
BISOPROLOL (425)
Which ALLOPURINOL Alternatives Have Lower Lactic acidosis Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN