Does ALLOPURINOL Cause Malaise? 321 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 321 reports of Malaise have been filed in association with ALLOPURINOL (Allopurinol). This represents 1.7% of all adverse event reports for ALLOPURINOL.
321
Reports of Malaise with ALLOPURINOL
1.7%
of all ALLOPURINOL reports
35
Deaths
195
Hospitalizations
How Dangerous Is Malaise From ALLOPURINOL?
Of the 321 reports, 35 (10.9%) resulted in death, 195 (60.7%) required hospitalization, and 41 (12.8%) were considered life-threatening.
Is Malaise Listed in the Official Label?
Yes, Malaise is listed as a known adverse reaction in the official FDA drug label for ALLOPURINOL.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Malaise?
ADALIMUMAB (15,965)
ETANERCEPT (13,600)
METHOTREXATE (9,970)
TOFACITINIB (9,040)
SECUKINUMAB (8,570)
INFLIXIMAB (7,477)
RITUXIMAB (6,587)
PREGABALIN (6,320)
PREDNISONE (6,319)
ABATACEPT (6,251)
Which ALLOPURINOL Alternatives Have Lower Malaise Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN