Does ALLOPURINOL Cause Nephrolithiasis? 74 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 74 reports of Nephrolithiasis have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.4% of all adverse event reports for ALLOPURINOL.
74
Reports of Nephrolithiasis with ALLOPURINOL
0.4%
of all ALLOPURINOL reports
0
Deaths
52
Hospitalizations
How Dangerous Is Nephrolithiasis From ALLOPURINOL?
Of the 74 reports, 52 (70.3%) required hospitalization, and 7 (9.5%) were considered life-threatening.
Is Nephrolithiasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 74 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Nephrolithiasis?
ADALIMUMAB (2,416)
ETANERCEPT (1,292)
INFLIXIMAB (981)
METHOTREXATE (979)
ABATACEPT (788)
TOPIRAMATE (768)
CERTOLIZUMAB PEGOL (735)
RITUXIMAB (709)
TOFACITINIB (699)
SODIUM OXYBATE (698)
Which ALLOPURINOL Alternatives Have Lower Nephrolithiasis Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN