Does ALLOPURINOL Cause Pancytopenia? 385 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 385 reports of Pancytopenia have been filed in association with ALLOPURINOL (Allopurinol). This represents 2.0% of all adverse event reports for ALLOPURINOL.
385
Reports of Pancytopenia with ALLOPURINOL
2.0%
of all ALLOPURINOL reports
74
Deaths
267
Hospitalizations
How Dangerous Is Pancytopenia From ALLOPURINOL?
Of the 385 reports, 74 (19.2%) resulted in death, 267 (69.4%) required hospitalization, and 50 (13.0%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
Yes, Pancytopenia is listed as a known adverse reaction in the official FDA drug label for ALLOPURINOL.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which ALLOPURINOL Alternatives Have Lower Pancytopenia Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN