Does ALLOPURINOL Cause Sciatica? 17 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 17 reports of Sciatica have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.1% of all adverse event reports for ALLOPURINOL.
17
Reports of Sciatica with ALLOPURINOL
0.1%
of all ALLOPURINOL reports
16
Deaths
16
Hospitalizations
How Dangerous Is Sciatica From ALLOPURINOL?
Of the 17 reports, 16 (94.1%) resulted in death, 16 (94.1%) required hospitalization, and 14 (82.4%) were considered life-threatening.
Is Sciatica Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 17 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Sciatica?
ADALIMUMAB (2,253)
METHOTREXATE (1,745)
TOCILIZUMAB (1,681)
RITUXIMAB (1,671)
ABATACEPT (1,621)
ETANERCEPT (1,583)
INFLIXIMAB (1,449)
HYDROXYCHLOROQUINE (1,430)
PREGABALIN (1,411)
LEFLUNOMIDE (1,394)
Which ALLOPURINOL Alternatives Have Lower Sciatica Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN