Does ALLOPURINOL Cause Type iv hypersensitivity reaction? 20 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 20 reports of Type iv hypersensitivity reaction have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.1% of all adverse event reports for ALLOPURINOL.
20
Reports of Type iv hypersensitivity reaction with ALLOPURINOL
0.1%
of all ALLOPURINOL reports
1
Deaths
15
Hospitalizations
How Dangerous Is Type iv hypersensitivity reaction From ALLOPURINOL?
Of the 20 reports, 1 (5.0%) resulted in death, 15 (75.0%) required hospitalization, and 4 (20.0%) were considered life-threatening.
Is Type iv hypersensitivity reaction Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 20 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Type iv hypersensitivity reaction?
AMOXICILLIN (165)
CLINDAMYCIN (128)
INFLIXIMAB (120)
CEFACLOR (101)
IBUPROFEN (98)
AMPICILLIN (97)
VANCOMYCIN (97)
CEPHALEXIN (92)
AMOXICILLIN\CLAVULANIC ACID (89)
CEFUROXIME (82)
Which ALLOPURINOL Alternatives Have Lower Type iv hypersensitivity reaction Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN