ALTEPLASE for Prophylaxis: Side Effects & Safety Data
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There are 8 adverse event reports in the FDA FAERS database where ALTEPLASE was used for Prophylaxis.
Most Reported Side Effects for ALTEPLASE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| No adverse event | 2,456 | 19.4% | 0 | 17 |
| Off label use | 1,752 | 13.8% | 137 | 135 |
| Gingival bleeding | 1,018 | 8.0% | 18 | 44 |
| Cerebral haemorrhage | 819 | 6.5% | 357 | 232 |
| Death | 818 | 6.5% | 818 | 58 |
| Haemorrhage intracranial | 615 | 4.9% | 247 | 143 |
| Angioedema | 603 | 4.8% | 37 | 192 |
| Haemorrhage | 536 | 4.2% | 172 | 107 |
| Drug ineffective | 524 | 4.1% | 69 | 99 |
| Haemorrhagic transformation stroke | 496 | 3.9% | 168 | 127 |
| Product storage error | 371 | 2.9% | 1 | 2 |
| Intercepted medication error | 244 | 1.9% | 0 | 0 |
| Hypotension | 242 | 1.9% | 48 | 80 |
| Intercepted product storage error | 227 | 1.8% | 0 | 0 |
| Vomiting | 224 | 1.8% | 25 | 76 |
Other Indications for ALTEPLASE
Ischaemic stroke (2,786)
Product used for unknown indication (2,073)
Cerebrovascular accident (1,630)
Cerebral infarction (1,334)
Thrombolysis (1,142)
Pulmonary embolism (617)
Acute myocardial infarction (610)
Myocardial infarction (193)
Device occlusion (179)
Complication associated with device (168)
Other Drugs Used for Prophylaxis
PEGFILGRASTIM (7,424)
HUMAN C1-ESTERASE INHIBITOR (5,950)
DENOSUMAB (4,541)
SULFAMETHOXAZOLE\TRIMETHOPRIM (3,197)
ASPIRIN (2,083)
VALACYCLOVIR (1,574)
PANTOPRAZOLE (1,502)
VARICELLA-ZOSTER VIRUS STRAIN OKA/MERCK LIVE ANTIGEN (1,444)
CLOPIDOGREL BISULFATE (1,296)
ENOXAPARIN (1,278)