Does ALTEPLASE Cause Hypersensitivity? 85 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 85 reports of Hypersensitivity have been filed in association with ALTEPLASE (Activase). This represents 0.7% of all adverse event reports for ALTEPLASE.
85
Reports of Hypersensitivity with ALTEPLASE
0.7%
of all ALTEPLASE reports
4
Deaths
17
Hospitalizations
How Dangerous Is Hypersensitivity From ALTEPLASE?
Of the 85 reports, 4 (4.7%) resulted in death, 17 (20.0%) required hospitalization, and 12 (14.1%) were considered life-threatening.
Is Hypersensitivity Listed in the Official Label?
Yes, Hypersensitivity is listed as a known adverse reaction in the official FDA drug label for ALTEPLASE.
What Other Side Effects Does ALTEPLASE Cause?
No adverse event (2,456)
Off label use (1,752)
Gingival bleeding (1,018)
Cerebral haemorrhage (819)
Death (818)
Haemorrhage intracranial (615)
Angioedema (603)
Haemorrhage (536)
Drug ineffective (524)
Haemorrhagic transformation stroke (496)
What Other Drugs Cause Hypersensitivity?
ETANERCEPT (10,846)
ADALIMUMAB (10,641)
METHOTREXATE (9,799)
TOCILIZUMAB (9,076)
ABATACEPT (8,945)
INFLIXIMAB (8,519)
RITUXIMAB (8,408)
ADAPALENE (8,356)
LEFLUNOMIDE (7,926)
CERTOLIZUMAB PEGOL (7,353)
Which ALTEPLASE Alternatives Have Lower Hypersensitivity Risk?
ALTEPLASE vs ALTERNARIA ALTERNATA
ALTEPLASE vs ALTHIAZIDE
ALTEPLASE vs ALTHIAZIDE\SPIRONOLACTONE
ALTEPLASE vs ALUMINUM
ALTEPLASE vs ALUMINUM HYDROXIDE